REVERSIBLE ALTERATIONS IN THE NEUROMUSCULAR JUNCTIONS OF DROSOPHILA M E L A N O G A S T E R BEARING A TEMPERATURE-SENSITIVE MUTATION, shibire

In this s tudy we r epo r t a re la t ionship b e t w e e n the u l t ras t ructure of the neuromuscular junct ions of t ibial muscles and the t e m p e r a t u r e i n d u c e d paralysis in s h i b i r e flies. The re is a decrease in the n u m b e r of synapt ic vesicles of neu romuscu la r junc t ions in flies which are held at or above 29~ Short ly af ter r e tu rn to 22~ the synapt ic vesicles are again p resen t in large numbers . Pr io r t r e a tmen t wi th t e t rodo tox in o r ba rb i tu ra te pro tec ts the junc t ions f rom the t empe ra tu r e i nduced change in morpho logy .